ProJect Pharmaceuticals?offers pharmaceutical development of ADCs and other cytotoxic drugs in a new safety laboratory with predictive analytical methods and high end freeze drying capabilities implemented.

The ability to develop Antibody Drug Conjugates?(ADCs) by combining protein formulation and process know how with cytotoxic drug expertise puts ProJect Pharmaceutics in a unique position within the biopharmaceutical industry. The company’s new safety facilities in dedicated labs and a deep understanding of the challenges when processing highly potent drugs enable us to provide specific solutions for ADCs and other cytostatic agents.

Many pharmaceutical ingredients of this class show limited solubility in water and degrade rapidly during compounding, filling and freeze-drying.?ADCs in particular have a lower thermodynamic and colloidal stability due to the attachment of hydrophobic drug moieties leading to modified charge pattern and stronger hydrophobic interactions. Reduced solubility and a pronounced tendency to aggregation and denaturation may be the consequences. ProJect Pharmaceutics?s Predictive Formulation Analytics is the proven technology to quickly and reliably identify promising formulation candidates for ADCs and to overcome drug specific stability issues.

Fraunhoferstra?e 22
D ? 82152 Martinsried


Web: ProJect Pharmaceutics GmbH

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