Scientific Narratives I – M

I

Ibritumomab

Ibritumomab Tiuxetan

ICRF-187 (Also see Cardioxane? and dexrazoxane) Idamycin?

Idarubicin

Ifex?

IFN-alpha

Ifosfamide

IL-11

IL-2 (Also see: Aldesleukin, rIl-2, Interleukin-2 and Proleukin?)

Imatinib mesylate

Imidazole Carboxamide

Interferon alfa

Interferon Alfa-2b (PEG Conjugate)

Interleukin-2 (Also see: Aldesleukin, IL-2, rIL2 and Proleukin?)

Interleukin-11

Intron A? (interferon alfa-2b)

Iressa?

Irinotecan

Isotretinoin

Istodax? (romidepsin)
A member of a class of cancer drugs known as histone deacetylase (HDAC) inhibitors. HDACs catalyze the removal of acetyl groups from acetylated lysine residues in histones, resulting in the modulation of gene expression. HDACs also deacetylate non-histone proteins, such as transcription factors. HDAC inhibitors can be divided into four main classes: cyclic tetrapeptides (I), short-chain fatty acids (II), hydroxamic acids (III), and benzamides (IV). The cyclic peptide structure of ISTODAX is novel among the cyclic tetrapeptides. In vitro, romidepsin causes the accumulation of acetylated histones, and induces cell cycle arrest and apoptosis of some cancer cell lines. For full prescribing information, visit Istodax?.

Ixabepilone

Ixempra?

J

K

Kidrolase?

L
Lanacort?

Lapatinib

L-asparaginase

LCR

Lenalidomide

Letrozole

Leucovorin

Leukeran

Leukine?

Leuprolide

Leurocristine

Leustatin?

Liposomal Ara-C

Liquid Pred?

Lomustine

L-PAM

L-Sarcolysin

Lupron?

Lupron Depot?

M

Matulane?

Maxidex

Mechlorethamine

Mechlorethamine Hydrochloride

Medralone?

Medrol?

Megace?

Megestrol

Megestrol Acetate

Melphalan

Mercaptopurine

Mesna Mesnex?

Methotrexate

Methotrexate Sodium

Methylprednisolone

Meticorten?

Mitomycin

Mitomycin-C

Mitoxantrone

M-Prednisol?

MTC

MTX

Mustargen?

Mustine

Mutamycin?

Myleran?

Mylocel?

Mylotarg?

Last update: January 14, 2012