Innate Pharma, a French biopharmaceutical company founded in 1999, is developing first-in-class immunotherapy drugs for cancer and inflammatory diseases. The company’s drug-candidates belong to a new class of therapeutic agents and consist of monoclonal antibodies aimed at immune regulatory checkpoints with a unique focus on the innate immunity compartment.
Innate Pharma develops drug candidates with immuno-stimulating properties in cancer and with immuno-blocking properties in inflammatory conditions. Furthermore, many of the ligands to the innate immunity receptors are expressed on tumor cells, opening the way to the development of directly cytotoxic antibodies.
The company’s most advanced drug-candidates are licensed to major biopharmaceutical groups. Lirilumab (IPH2102/BMS-986015) currently in Phase I clinical trial (NCT01714739) in cancer. The purpose of this study is to assess the safety and tolerability of Lirilumab given in combination with BMS-936558 and to identify dose limiting toxicities (DLTs) and the maximally tolerated dose (MTD) of the combination, in subjects with advanced (metastatic and/or unresectable) solid tumors. The drug is licensed to Bristol-Myers Squibb. Another drug, and IPH2201, developed in inflammation and currently in a Phase I clinical trial in rheumatoid arthritis, is licensed to Novo-Nordisk A/S, one of the company’s major shareholders.
117 Avenue de Luminy
13276 Marseille
France
Web: Innate Pharma, S.A.
