The Chemistry Research Solution, LLC (TCRS) has ample experience in providing antibody-drug conjugate (ADC) related services to its clients. Currently, the company is engaged in supporting several biotech and pharmaceutical companies in the development of their ADC development programs.?TCRS has a variety of highly potent “warheads” or payloads in stock for advancing its clients’ ADC projects. A selection of cleavable and non-cleavable linkers and spacer molecules is also available.
The company offers a variety of services, including:
- Preparation of ADCs, Antibody-Enzyme and Antibody-Liposome conjugates
- Design and synthesis of potent cytotoxic compounds and payloads with linkers
- Customized design and synthesis of generic linkers
- Preparation and purification of bioconjugates from milligram- to gram- scale
- Modification of carbohydrates, polysaccharides, and glycoconjugates
- Preparation of fluorescent probes.
TCRS conducts all work with highly toxic/cytotoxic compounds and payloads in its specially designed containment laboratory, which is accessible only to authorized and trained chemists. This laboratory has an independent air-handling (HVAC) system and is equipped with certified chemical fume hoods, HEPA-filtered ventilation and enclosed, HEPA-ventilated weighing stations. Compounds of high toxicity are handled in a glove box with a closed-loop containment (CLC) system that operates under negative pressure.
360 George Patterson Blvd.
Suite 108
Bristol, PA 19007
U.S.A.
Web:?The Chemistry Research Solution, LLC
