Viventia Bio Inc. is developing and advancing the next generation of human antibody-based therapeutics for use in oncology. The company’s approach combines the specificity of an antibody with the potency of a cytotoxic payload to provide targeted therapies for the safer and more efficacious treatment of cancer patients.
Viventia has developed a potent payload called deBouganin. When coupled to a targeting antibody this drug can effectively kill cancer cells without harming normal cells. This differential targeting enhances the therapeutic potential of Viventia’s drugs and provides prolonged clinical benefit. deBouganin has been chemically conjugated to full length antibodies as well as fused to numerous antibody fragments and has been found to be safe and efficacious in the clinic.
Viventia has built a product pipeline using its innovative antibody discovery platform, IDAP (Immune Driven Antibody Platform). IDAP is a collection of technologies designed to create a portfolio of fully human cancer specific antibodies and identify novel oncology drug targets on the surface of cancer cells. The company has 3 products in clinical development, VB6-845, Vicinium? and Proxinium?. VB6-845, a deBouganin therapeutic designed for the systemic treatment of various EpCAM-positive solid tumors. VB6-845 has undergone exploratory investigation in a Phase I clinical trial and was shown to be safe and well-tolerated. Vicinium? and Proxinium? are used for the treatment of non-muscle invasive bladder cancer and squamous cell cancer of the head & neck, respectively. Both have successfully completed Phase II trials.
147 Hamelin Street
Winnipeg, MB
R3T 3Z1
Canada
Web: Viventia Bio Inc.
