Varian’s Adaptive Therapy Provides Opportunity to Transform Radiation Oncology

Millenium Park, Chicago. Courtesey: 2018 Fotolia, Used with Permission.
Millenium Park, Chicago. Courtesey: 2018 Fotolia, Used with Permission.

Ethos™ therapy, an Adaptive Intelligence™ solution developed by Varian, is an artificial intelligence (AI)-driven holistic solution designed to increase the capability, flexibility and efficiency of radiotherapy. According to the manufacturer, the new solution is designed to deliver an entire adaptive treatment in a typical 15-minute time-slot, from patient setup through treatment delivery.

Varian’s Adaptive therapy was unveiled during the 2019 annual meeting of the American Society for Radiation Oncology (ASTRO), held from September 15 – 18, 2019 at McCormick Place – West Building, Chicago, Illinois.

The system provides the ability to alter the treatment plan based on tumor and anatomical changes. The goal is to better target the tumor, reduce dose to healthy tissue and potentially improve overall outcomes.

The streamlined workflow of Ethos therapy is enabled by its AI-driven planning and contouring capabilities.

The treating physician defines his or her clinical intent using predefined templates. Then an initial treatment plan is generated based and adapted in response to the variability of the tumor’s shape and cellular characteristics, along with fluctuations in the tumor’s position due to changes in nearby organs.

The ability of Ethos to deliver on-couch adaptive treatment puts the patient at the center of care.

Ethos™ therapy, an Adaptive Intelligence™ solution developed by Varian, is an artificial intelligence (AI)-driven holistic solution designed to increase the capability, flexibility and efficiency of radiotherapy

Multimodality images
One of the strong Ethos therapy offers the use of multimodality images (MR, PET, CT), and daily iterative CBCT images at the console. By providing an up-to-date view of the patient’s anatomy, Ethos therapy provides clinicians the confidence to make more informed adaptive treatment decisions. The solution is built on Varian’s latest treatment delivery technology and provides fast imaging and treatment delivery without compromising quality.

“Every patient deserves access to the best and most personalized cancer care,” said Chris Toth, president Varian Oncology Systems.

“Adaptive therapy is the future of personalized radiation therapy. Beginning with IMRT we were able to shape dose with more fidelity, and then image guided radiation therapy (IGRT) allowed us to target with more precision. Ethos therapy, powered by AI, will allow us to adapt and personalize dose to every patient, every day in a typical treatment timeslot. This is a transformational moment for cancer care,” Toth added

To advance the worldwide adoption of intelligent adaptive therapy, Varian formed the Adaptive Intelligence Consortium in April 2019. The Adaptive Intelligence Consortium will lead clinical trials to develop evidence-based clinical protocols for Varian’s adaptive radiotherapy solution and minimize the need for individual clinics to develop their own methods and practices.

Participants include clinicians and scientists from leading cancer clinics across the globe. The consortium will lead clinical trials to develop evidence-based clinical protocols for Ethos therapy.

Earlier this year Varian’s Ethos therapy has received CE mark and is currently 510(k) pending and not for sale in all markets.